Associate/Scientist Analytical Development, Mass Spectrometry (m/f/d)

We are seeking an experienced and highly motivated Scientist with expertise in LC-MS characterization and analytical method development. This is a hands-on, laboratory-based role with responsibilities including LC-MS development, qualification, and routine analysis. The successful candidate will collaborate closely with multidisciplinary teams across ProtaGene and with external pharmaceutical clients to deliver high-quality analytical solutions and support client programs.

Your Responsibilities

• Perform LC-MS characterization of biologics: prepare samples (SPE, IP, LLE), run chromatography and mass spectrometry experiments, and generate data that supports client programs.

• Support lab operation, and the maintenance, qualification, and troubleshooting of LC-MS instrumentation and other laboratory equipment.

• Independently design and execute laboratory studies, analyze and interpret data, troubleshoot analytical challenges, and communicate findings through technical reports, presentations, and team discussions.

• Maintain accurate and compliant laboratory records, electronic laboratory notebooks (ELNs), experimental protocols, and supporting documentation in accordance with company procedures and quality standards.

• Prepare, qualify, and maintain assay reagents, reference standards, controls, and other materials required to support analytical testing activities.

• Prepare, review, and present project updates, technical data, and study results to internal teams and external clients.

• Continuously expand technical expertise and develop analytical skills to support emerging assays and characterization strategies for biologics, gene therapy, and cell therapy programs.

• Collaborate effectively with multidisciplinary teams to ensure the timely delivery of high-quality analytical results and project milestones.

• Bachelor’s degree in Chemistry, Biochemistry, or a related scientific discipline with 3–5 years of relevant laboratory experience, or a Master’s degree with 1–3 years of relevant experience.

• Demonstrated hands-on experience with LC-MS analysis of biological samples, including protein extraction and digestion, peptide cleanup and separation, instrument operation, LC-MS acquisition method development, and data analysis is required.

• Prior experience in the biotechnology, pharmaceutical, or related life sciences industry is strongly preferred.

• Proficiency with Thermo Orbitraps and software is a strong plus.

• Working knowledge of biotherapeutic analytical development  (e.g., method qualification and assay transfer) is a plus. 

• Ability to independently plan and execute experiments while managing multiple priorities and maintaining timelines in a fast-paced  environment.

• Ability to work successfully in both a team/matrix environment as well as independently.

• Experience with the analytical characterization of oligonucleotides, ADCs, and AOCs a plus.
  

What we offer

• Benefits: Comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

• Work Environment: Laboratory-based position in a fast-paced, growth-oriented environment.